JARED - JOINT ACTION ON RESPIRATORY DISEASES

Project No. 101183391

Program: EU4Health Programme (EU4H) Topic: EU4H-2023-JA-3-IBA-03

Project budget: EUR 5 999 999,93 EU Grant 80% for project - EUR 4 799 999.95,  VUH Santaros klinikos received  EUR100 045.86

Responsible Department at VUH Santaraos Klinikos:

Project Manager: Prof. Edvardas.Danila,

Project Purpose  - to mitigate the impact of chronic respiratory diseases (CRDs) within Europe. It uniquely combines innovative digital health technologies, improved access to diagnostic tools, and enhanced health literacy efforts to address and manage CRDs effectively. This initiative is grounded in a collaborative approach, engaging various healthcare stakeholders to promote preventive strategies and reduce the overall burden and mortality rates associated with these diseases. By focusing on the integration of environmental and lifestyle factors, the project aims to offer a holistic solution to CRDs. Additionally, the JARED project prioritizes inclusivity, ensuring that vulnerable populations receive significant attention throughout its implementation. The JARED project is poised to deliver significant impacts across the short, medium, and long term. In the immediate future, it will establish robust evaluation frameworks, enhance CRD management knowledge through educational materials, and initiate key stakeholder engagements. This comprehensive strategy targets not only the immediate alleviation of CRD burdens but also the systemic transformation of healthcare approaches and policy frameworks for chronic respiratory diseases.

Santaros klinikos participates in Work Package 6 (WP 6) following tasks - T6.3 Interstitial lung diseases (modifiable risk factors)  T.6.4  T6.4 Early detection, diagnosis and treatment of chronic respiratory diseases

Project Co-ordinator: ORSZAGOS KORANYI PULMONOLOGIAI INTEZET (Hungary)

Project Partners:

BORSOD-ABAUJ-ZEMPLEN VARMEGYEI KOZPONTI KORHAZ ES EGYETEMI OKTATO KORHAZ (Hungary)

NEMZETI NEPEGESZSEGUGYI ES GYOGYSZERESZETI KOZPONT (Hungary)

1ST YGEIONOMIKI PERIFEREIA DYPE ATTIKIS (Greece)

GENIKO NOSOKOMEIO NOSIMATON THORAKOS ATHINON I SOTIRIA (Greece)

SERVICIO ANDALUZ DE SALUD (Spain)

FUNDACION INSTITUTO DE INVESTIGACION MARQUES DE VALDECILLA (Spain)

FUNDACION INSTITUTO DE ESTUDIOS DE CIENCIAS DE LA SALUD DE CASTILLA Y LEON  (Spain)

FUNDACION PARA LA INVESTIGACION DE MALAGA EN BIOMEDICINA Y SALUD (Spain)

FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO 12 DE OCTUBRE (Spain)

FUNDACIO DE RECERCA CLINIC BARCELONA-INSTITUT D INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (Spain)

FUNDACION PARA LA INVESTIGACION DEL HOSPITAL CLINICO DE LA COMUNITAT VALENCIANA, FUNDACION INCLIVA (Spain)

NARODOWY FUNDUSZ ZDROWIA (Poland)

WARSZAWSKI UNIWERSYTET MEDYCZNY (Poland)

TERVEYDEN JA HYVINVOINNIN LAITOS (Finland)

FILHA RY (Finland)

AARHUS KOMMUNE (Demark)

KLINICKI BOLNICKI CENTAR ZAGREB (Croatia)

ISTITUTO SUPERIORE DI SANITA  (Italy)

UNIVERSITA POLITECNICA DELLE MARCHE (Italy)

UNIVERSITA DEGLI STUDI DI FIRENZE (Italy)

UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II (Italy)

SLIMIBU PROFILAKSES UN KONTROLES CENTRS (Latvia)

PAULA STRADINA KLINISKA UNIVERSITATES SLIMNICA (Latvia)

RIGAS STRADINA UNIVERSITATE (Latvia)

LIETUVOS RESPUBLIKOS SVEIKATOS APSAUGOS MINISTERIJA (Lithuania)

NACIONALINIS VISUOMENES SVEIKATOS CENTRAS PRIE SVEIKATOS APSAUGOS MINISTERIJOS (Lithuania)

LIETUVOS SVEIKATOS MOKSLU UNIVERSITETAS (Lithuania)

VIESOJI ISTAIGA VILNIAUS UNIVERSITETO LIGONINE SANTAROS KLINIKOS (Lithuania)

"INSTITUTIA MEDICO-SANITARA PUBLICA - INSTITUTUL DE FTIZIOPNEUMOLOGIE "CHIRIL DRAGANIUC" (Moldova)

MINISTERIO DA SAUDE (Portugal)

UNIDADE LOCAL DE SAÚDE SANTA MARIA  (Portugal)

INSTITUTO NACIONAL DE SAUDE DR. RICARDO JORGE (Portugal)

INSTITUTUL DE PNEUMOFTIZIOLOGIE MARIUS NASTA (Romania)

REYKJALUNDUR ENDURHAEFINGARMIDSTODSIBS FELAGASAMTOK (Icland)

MINISTERSTVO ZDRAVOTNICTVI CESKE REPUBLIKY (Czeckia)

DEBRECENI EGYETEM (Hungary)

NATIONAL INSTITUTE OF PHTHISIOLOGY AND PULMONOLOGY NAMED AFTER F. G. YANOVSKY OF THE NAMS OF UKRAINE (Ukrain)

 

Project Start – 01 December 2024

Project End – 30 November 2027

 

 

Collaborative Innovation Procurement Action to Improve the Efficiency, Quality and Sustainability of Healthcare (EcoQUIP Plus)
EcoQUIP Plus is a collaborative Public Procurement of Innovation (PPI) project aimed at demonstrating how pro- innovation procurement methods can improve the efficiency, quality and sustainability of healthcare.
 
Many hospitals across Europe do not have an effective emergency call system, in cases such as emergency intubation and resuscitation where rapid help is needed. Help is often called in a confused and chaotic way which is stressful for staff and, moreover, life threatening for patients. Delays in the right support arriving can adversely affect the patients outcomes and can lead to unnecessary clinical complications. Speedy and efficient arrival of help in such situations would lead to a significant improvement in patient outcomes, improve the use of staff resources, and significantly reduce stress for staff. In addition, a smart solution would enable the collation and analysis of data to enable learning and further improve outcomes. 
The solution should be able to alert the specifically required staff 24/7 and direct them to where they are needed. The solution will also collate and facilitate an analyse of data that will lead to learning and further improvements in the system and patient/staff outcomes.
 
Coordinator: OPTIMAT LIMITED (UK).

Partners: Vilnius University Hospital Santaros Klinikos (VULSK), Agency for Science, Innovation and Technology (LT), Jera Consulting Limited (UK), University Hospitals Bristol Nhs Foundation Trust (UK), Zespol Opieki Zdrowotnej W Suchej Beskidzkiej (Poland), Azienda Ospedaliero Universitaria Policlinico S. Orsola Malpighi (Italy ), Agencia De Qualitat I Avaluacio Sanitaries De Catalunya (Spain), Corporacio Sanitaria Parc Tauli De Sabadell (Spain), European Health Management Association (Belgium), Synoptic Technologies Ltd (UK).

Twinning in Research and Education to improve survival in Childhood Solid Tumours in Lithuania (TREL)
2021 10 21 About TREL PROJECT 

______________________________________________________________________________________
Twinning in Research and Education to improve survival in Childhood Solid Tumours in Lithuania (TREL)
Solid tumours can occur in many parts of the body and there are some types that develop only in children. VULSK coordinates the EU-funded TREL project which aims to enhance translational, clinical and late-effect research in paediatric solid tumours.
 
The purpose of the project: increase the research excellence of VULSK and to enhance its reputation, attractiveness and networking channels in the field of pediatric solid tumours. By twinning with eight internationally-leading research institutions from across Europe, VULSK will be positioned to improve its scientific, technical and innovation capacities in translational and clinical research.
 
Coordinator: Vilnius University Hospital Santaros Klinikos. 

Partners: Children’s Cancer Research Institute (Austria), University Medical Center Hamburg-Eppendorf (Germany), Region Hovedstaden (Denmark), Princess Maxima Centre (Netherlands), Instituto Giannina Gaslini (Italy), Consorzio Interuniversitario (Italy), Institute Gustave Roussy (France), European Society for Paediatric Oncology (Belgium).
 
For more information, please follow the link: https://cordis.europa.eu/project/id/952438



Contacts:

Coordinator Local Team

Project coordinators dr. Jelena Rascon jelena.rascon@santa.lt

Project manager Renata Blackutė renata.blackute@santa.lt

Coordinator assistant Alma Čerkauskienė alma.cerkauskiene@santa.lt

CHRODIS PLUS: Implementing good practice for chronic diseases
The economic burden of non-communicable diseases (NCDs) is on the rise and is projected to show steeper increases in the future, especially in less developed economies and among the poor in middle- and high-income countries. CHRODIS+ during its 36 months of operation will contribute to the reduction of this burden by promoting the implementation of policies and practices with demonstrated success. The development and sharing of these tested policies and projects across EU countries is the core idea driving this action.

The purpose of the project: promote the implementation in several countries of innovative policies and practices for patient empowerment, health promotion and prevention, and fostering quality management of CD and multimorbidity as well as for improving the adaptation of the employment sector to chronic patients, in pilot actions that can be validated before scaling them up.
 
Coordinator INSTITUTO DE SALUD CARLOS III (Spain).

Scientific Coordinator: Vilnius University Hospital Santaros Klinikos. 

Participants: 42 beneficiaries representing 20 European countries.

Scientific project coordinator - Rokas Navickas, Project Manager - Elena Jureviciene.
 
For more information, please follow the link http://chrodis.eu/
       
Personalised Knowledge Transfer and Access to Tailored Evidence-Based Assets on Integrated Care: SCIROCCO Exchange
The SCIROCCO Exchange project builds upon the preliminary achievements of the B3 Action Group on Integrated Care (of the European Innovation Partnership on Active and Healthy Ageing) that first developed the concept of the B3 Maturity Model. Through the activities of the EU Health Programme funded project SCIROCCO, the Model has been further refined and tested and is supported by a validated online self-assessment tool for integrated care. The capacity-building support will be provided to 9 national and regional health care institutions having a different maturity level and organization of integrated care. 

The purpose of the project: support health and social care authorities in the adoption and scaling-up of integrated care, maximize the value and impact of the SCIROCCO tool for regions and organizations involved in the deployment of integrated care.
 
Coordinator: Scottish Government (UK)

Partners: 14 partners from 10 countries including national and regional health care institutions, universities, competence centers and etc.

Vilnius University Hospital Santaros Klinikos Project Manager - Elena Jureviciene.

For more information, please follow the link: ww.sciroccoexchange.com


      
Reduction of social exclusion and increase in the quality of life of cancer patients in Vilnius and Grodno regions

Morbidity of the bladder, kidney, cervical, uterine body, upper urinary tract urothelial, ovary, prostate and colon cancer cases represent a major proportion of all cancer cases in Lithuania and Belarus, Vilnius and Grodno regions are not an exception. Radical surgery treatment applied to the cancer patients is related with long postoperative treatment and higher risk of complications. All this leads to the worsening of the patient's quality of life both in the postoperative period and later, experienced social exclusion and long-term patient's disability related to the higher risk of poverty. 

Seeking to improve the quality of life of cancer patients’ who are certainly identified as vulnerable group it is appropriate to increase the access to the minimally invasive surgery services. Application of these services leads to shorter hospitalization, lower probability of postoperative complications, and faster return to the normal activities. 

The purpose of the project: to establish and  strengthen cooperation between Lithuania and Belarus, to exchange experiences in order to reduce social exclusion and improve the quality of life of cancer patients in Vilnius and Grodno regions, to increase access to minimally invasive surgery services in urology, abdominal surgery, and gynecology fields.

Coordinator: Vilniaus universiteto ligonine Santaros klinikos.

Project partner: Grodno University Clinic.

Network for blood pressure research in children and adolescents (HyperChildNET)
Hypertension is now responsible for 7.1 million deaths per year worldwide, and largely contributes to cardiovascular and renal diseases such as ischemic heart disease, stroke and chronic kidney disease. Cardiovascular and renal diseases linked to high blood pressure are the first cause of mortality in Europe. High blood can also become evident in early life. But relatively little attention has been paid to the problem of hypertension in children and adolescents.
 
The purpose of the project: establish a European sustainable and multidisciplinary network of internationally renowned researchers, clinicians, early career investigators, health economists, decision-makers, patients, regulatory bodies, nutrition & pharma companies and medical devices manufacturers focusing on acquiring a holistic understanding of the factors affecting high blood pressure (BP) in children in order to propose and implement corrective and preventive actions both globally and locally.
 
VULSK Project Managers: prof. Augustina Jankauskiene, dr. Karolis Azukaitis
 
For more information, please follow the link: https://www.cost.eu/actions/CA19115/#tabs|Name:overview

The European Researchers' Network Working on Second Victims
Every year between 8 and 12% of the people admitted to hospitals and around 6% of those in primary care suffer from an adverse event (AE) while receiving healthcare. When an AE does occur, there is a domino effect with healthcare professionals (second victims of these events) also suffering from the knowledge of having harmed their patients (first victims). This second victim phenomenon increases the likelihood of further errors and suboptimal care as consequences of emotional disturbances in the hours after the patient safety event.

The purpose of the project: facilitate discussion and share scientific knowledge, perspectives, and best practices concerning adverse events (AEs) in healthcare institutions to implement joint efforts to support second victims (SVs), and to introduce an open dialogue and discussion among stakeholders about the consequences of the SV phenomenon based on a cross-national collaboration that integrates different disciplines and approaches.

VULSK Project Managers: prof. Augustina Jankauskiene, dr. Karolis Azukaitis

For more information, please follow the link: https://www.cost.eu/actions/CA19113/#tabs|Name:overview

PanCare studies of the scale-up and implementation of the digital Survivorship Passport to improve people-centred care for childhood cancer survivors
Almost 500,000 former childhood cancer patients (CCS) are now living in Europe. Compared to the general population, CCS represent a vulnerable population as they are at an increased risk of developing health problems, known as late effects, resulting in excess morbidity and mortality. Many survivors are unaware of their personal risk for specific late effects, which reduces their ability to manage their own follow-up care. Similarly, their treating healthcare professionals (HCPs) lack information about care required for CCS and access to treatment data from their childhood cancer. The Survivorship Passport (SurPass) is an innovative, digital tool, developed in previous EU-funded projects, that can be used to overcome these knowledge gaps to improve people-centred long-term survivorship care. Importantly, end users (CCS, HCPs) are integral to the research, represented by three key stakeholder networks (PanCare, SIOP Europe, CCI Europe).

PanCareSurPass will conduct a robust assessment of the implementation of the SurPass by first conducting a pre-implementation study in six countries (Austria, Belgium, Germany, Italy, Lithuania, Spain) representing three infrastructural scenarios in Europe.  Ethical, structural, organisational, economical, national, local, privacy issues, health systems, and particular national circumstances will be taken into account throughout. An Implementation Strategy will be developed and the SurPass will be updated and validated before use in an implementation study in the six countries. The study will look at a range of outcomes including CCS activation and empowerment, CCS/HCP satisfaction with the tool, feasibility and health economics. Based on the results of the study, a Prediction Model will be developed to promote and support future implementation of the SurPass across Europe.
 
The purpose of the project: leverage the digital transformation of healthcare to improve people-centred survivorship care by scaling up and implementing an interoperable SurPass v2.0 across Europe.
 
Coordinator: University Medical Center of Johannes Gutenberg-U Mainz (UMC-Mainz)

Partners: Vilnius University Hospital Santaros klinikos (VULSK) and 16 other international partners from Austria, Germany, Italy, Spain, Belgium.
 
VULSK Project Manager: doc. dr. Jelena Rascon.

Strengthening Blood Safety System in Georgia

The project supports public health policies and programmes of Georgia in the field of communicable diseases and blood transfusion. It upgrades national blood safety legislation and assesses blood banks. It is a Twinning of Lithuanian, Dutch and Georgian partners, where European colleagues help Georgian counterparts with strengthening national capacities and assisting in carrying out reorganization of blood transfusion service, establishing laboratories, establishing quality systems for blood establishments.

The purpose of the project: upgrade national blood safety legislation and strengthen national institutional capacities in accordance with European regulations and the Association Agreement, to provide equal safety standards of blood components across the nation, assure safety of blood related services and prevent the spread of blood borne infections by blood transfusion.

Coordinator: Vilnius University Hospital Santaros Klinikos.

Partners: Central Project Management Agency; National Blood Centre of Lithuania; National Public Health Surveillance Laboratory of Lithuania; The Hospital of Lithuanian University of Health Sciences Kauno klinikos; Vilnius University Hospital Santaros klinikos; Centre for Communicable Diseases and AIDS of Lithuania; Sanquin Blood Supply (Sanquin) of the Netherlands.

For more information, please follow the link: https://eu4georgia.ge/strengthening-blood-safety-system-in-georgia/

VACCELERATE - European Corona Vaccine Trial Accelerator Platform
Horizon 2020 “Coordination and Support Actions” regarding “Mobilisation of research funds in case of Public Health emergencies”.
 
The purpose of VACELERATE is to serve as single-entry point for all stakeholders in COVID-19 vaccine development (pharma, academia, European Commission, EMA, ECDC, national health authorities and others) for phase 2 and 3 trials in Europe. Address any research question of interest outside the big registration trials, such as vaccine efficacy in virus variants, trials in children, pregnant women, immuno-compromised patients, trials on combination of different vaccines etc.
 
Coordinator: Keln university hospital, Germany
 
Partners: Biomedicinske centrum Slovenskej akademie vied (SK); Centro Hospitalar Universitario Do Porto EPE (PT); Collaborative Center for Clinical Epidemiology and Outcomes Research (EL); Ecrin European Clinical Research Infrastructure Network (FR); European University Cyprus (CY); European Vaccine Initiative Ewiv (DE); Hacettepe Universitesi (TR); Institut National De La Sante Et De La Recherche Medicale (FR); Instituto De Salud Carlos Iii (ES); Karolinska Institutet (SE); Region Stockholm (SE); Faculty Of Medicine, University Of Belgrade (RS); Ministry Of Health (IL); Uniwersytet Medyczny W Bialymstoku (PL); Medizinische Universitaet Wien (AT); University College Dublin, National University Of Ireland, Dublin (IE); National University Of Ireland Galway (IE); Region Hovedstaden (DK); Universiteit Antwerpen (BE); Universitaet Bern (CH); Universitetet I Bergen (NO); Universitair Medisch Centrum Utrecht Netherlands; Universita Degli Studi Di Verona (IT); Universite De Paris (FR); Vilnius University Hospital Santaros Klinikos (LT)
 
For more information, please follow the link: https://vaccelerate.eu/
 
 
DIGITALIZATION AND ADAPTATION OF TF-CBT (TRAUMA-ORIENTED COGNITIVE BEHAVIOR THERAPY) FORADOLESCENTS IN LITHUANIA

Research shows that a significant number of children in Lithuania experience numerous potentially traumatizing events, including emotional, physical, or sexual abuse or neglect. These events place children at risk of developing dangerous mental health problems such as depression, post-traumatic stress disorder, anxiety, drug dependency, and behavioral problems. The establishment of timely evaluation and accessible treatments can therefore have significant benefits for children, families, and communities at large.

Project No. LT03-2-SADM-K01-045

Project financed:  2014-2021 European Economic Area (EEA) financial mechanisms program „Health“ More information about the financial mechanisms of the European Economic Area at www.norwaygrants.lt.
Project value: 248 455,32 Eur

End of the project: 2024 03 31   

Project administrator: VšĮ „Smart Health DIH"

Project partners: Vilnius University Hospital Santaros Klinikos Child Development Center, Department of Child Psychiatry, Management and Psychology Institute

Vilnius University Hospital Santaros Klinikos Project Manager: Jurgita Radzevičienė

Project purpose: in Lithuania to validate the methodology of assessing the traumatic experience of children aged 10-17 and trauma-focused cognitive-behavioral therapy (TF-CBT) for parents/caregivers and children, to create and test its digital solution.

The project is financed by 2014-2021 European economic area financial mechanism programme „Health“. Funding amount 223,609.79 Eur, applicant and partners own contribution 24,845.53 Eur, total project budget 248,455.32 Eur.

More information about financial mechanism of European economic area www.norwaygrants.lt.




NEWS

2024-04-16 Closing conference "Possibilities of helping children overcome traumatic experiences with the help of TF-CBT intervention" was held. 120 participants (including lecturers) participated in the conference. 

2024 -03-31 Project activities were completed. During the implementation of the project, various methodologies for assessing children's traumatic experience and related symptoms (for example, post-traumatic stress, dissociation, depression) were validated, and the effectiveness of trauma-focused cognitive behavioral therapy (TF-CBT) were tested clinicaly. The results confirmed that the methods can be used in Lithuania, and TF-CBT significantly reduces post-traumatic stress symptoms and post-traumatic cognitions. 

2024 – 03-28  the trainings of the project "Implementation of Children's Traumatic Experience Assessment and Intervention (TF-CBT) Methodologies in Lithuania" took place, 154 participants, specialists (social workers, psychologists, pedagogues, etc.) working with traumatized children and their families, of whom 141 passed test and received certificates.

2024-03-04 Publication „(Un)Recognized Trauma: Children’s Traumatic Experiences, Dissociative Symptoms, Moods, Post-Traumatic Stress, and Cognitions in Clinical and Non-Clinical Samples“submitted to journal „Children“. The findings revealed associations between potentially traumatic events and dissociation symptoms, PTSD, depressive moods and feelings, and post-traumatic cognitions in both clinical and non-clinical samples. 

2023-11-01  Data collection of a comparative sample is started in Vilnius county, with the aim of adapting tools for assessing children's traumatic experience and its consequences in Lithuania. 

2023-09-01 Data collection of a clinical samples started in the Children's Psychiatry Department of Santaros Klinikos. 

2023-04-01 – 2023-07-01 Digital tool  testing and improvement for the Children's Traumatic Experience Assessment and Intervention (TF-CBT) methodologies. 

2023-05-02 Vilnius Regional Research Ethics Committees granted permission (No. 2023/4-1499-963.) to start a biomedical study „Digitalization and Adaptation of TF-CBT (Trauma-Oriented Cognitive Behavior Therapy) for Adolescents in Lithuania“. 

2022-12-11 Introductory conference of the project "Implementation of Children's Traumatic Experience Assessment and Intervention (TF-CBTt) methodologies in Lithuania" was held.

2022-09-08 Cooperation agreement with the administration of Vilnius  City Municipality was signed

2022-06-23 Cooperation agreement with Vilnius City Social Service Centre was signed.

2022-06-07 A contract was signed with a UAB "PROIT", digital solution supplier for the assessment of children's traumatic experiences.

2022-04-21 Cooperation agreement with Kaunas District Social Service Centre signed.

NARRATIVE – Natural history, quality of life and patient-reported outcomes in vascular anomalies


NARRATIVE
– Natural history, quality of life and patient-reported outcomes in vascular anomalies

Project No. EJPRD23-014
Program: European Joint Program on Rare Diseases (EJP RD)

This project has received funding from Research Council of Lithuanian (GA No.  S-EJP RD-24-1)  partner of the EJP RD. The EJP RD initiative has received  funding from the European Union's Horizon 2020 research and innovation programme under grant agreement N°825575.

Project value: EUR 1,801,512 total, EUR 99,960 - out of the total budget is VUL Santaros klinikos project budget

Responsible department at VUH Santaraos Klinikos: Vascular Reconstructive and Endovascular Surgery Center

Project Manager: Dr. Birutė Vaišnytė

Project Purpose - is to learn about the natural history and risk of progression of vascular anomalies (VA). The consortium partners aim to pave the way for patients targeted treatment:
1. Define genotype/phenotype correlations, to identify subgroups for risk stratification.
2. Define natural history and risk of progression within well-defined genotypic/phenotypic subgroups of patients within VA.
3. Apply OVAMA scales and other patient-reported outcomes in a large cohort of patients with well-defined genotypes/phenotypes and in different age groups using a user-friendly app to facilitate responses. .
4. Compile side effects and changes in quality of life following standard-of-care treatment.
5. Disseminate results and ensure open access to research results.

Project Coordinator: Eulalia Baselga, Hospital Sant Joan de Deu/Fundación Sant Joan de Deu, Dermatology Department (Spain)

Project Partners:
Laurence M. Boon, Cliniques universitaires St Luc, Université Catholique de Louvain (Belgium)
Annouk Anne Bisdorff-Bresson, AP-HP nord, Hôpital Lariboisiere (Ferance)
Friedrich G. Kapp, University of Freiburg (Germany)
Andrea Diociaiuti, Bambino Gesù Children’s Hospital  (Italy)
Nader Ghaffarpour, Karolinska Institutet (Sween)
Birute Vaisnyte, Vilnius University Hospital Santaros Klinikos (Lithuania)

Project Start – 1st July, 2024

Project End – 30th June, 2027
 
TeleGraft - Natural history, quality of life and patient-reported outcomes in vascular anomalies

Project No. 101057673   

Program: HORIZON.2.1.5 - Tools, Technologies and Digital Solutions for Health and Care, including personalised medicine


Project Value: EUR 4 352 522.00 total budget, EUR 40 118 - is VUH Santaros klinikos project budget

Responsible Department at VUH Santaraos Klinikos: Vascular Reconstructive and Endovascular Surgery Center

Project Manager: Tomas Baltrūnas

Project Purpose - to develop a smart biomimetic arteriovenous graft for telemonitoring of home dialysis. Innovative device TeleGraft will be composed of two diagnostic parts to monitor and prevent dialysis complications. Pressure transmitters will be used to monitor blood flow and optical sensors to detect inflammation and infections. The data will be processed by AI machine learning models and displayed in an easy-to-understand dashboard for healthcare professionals. The data will allow online telemonitoring as well as consultations by remote healthcare professionals. This innovation will make home dialysis safe for patients, even in areas with poor infrastructure, where patients live far from hemodialysis clinics. 

The TeleGraft system will be demonstrated in an operational environment through a 2-stage randomized clinical trial enrolling 60 patients at 5 hospitals across Europe (in Denmark, Sweden, Lithuania, Spain, and Germany) and through a home hemodialysis field study.

Project Co-ordinator: SYDDANSK UNIVERSITET (SDU), Denmark

Project Partners:

VERIGRAFT AB (VERI), Sweden

BIOMODICS APS (BM), Denmark

LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V. (IPHT), Germany

REGION SYDDANMARK (OUH), Denmark

BMD SOFTWARE LDA (BMD), Portugal

PI VILNIAUS UNIVERSITETO LIGONINE SANTAROS KLINIKOS (VULSK), Lithuania

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN (TUM-MED), Germany

Servicio Vasco de Salud Osakidetza (OSA), Spain

ASOCIACION INSTITUTO DE INVESTIGACION SANITARIA BIOBIZKAIA, Spain

REGION STOCKHOLM (KUH), Sweden

ASTON UNIVERSITY, Great Britain

THE UNIVERSITY OF BIRMINGHAM, Great Britain

 

Project Start – 1 September 2022 

Project End – 28 February 2027

EUCARE - European Cohorts of Patients and Schools to Advance Response to Epidemics

EUCARE  - European Cohorts of Patients and Schools to Advance Response to Epidemics

 

Project No. 101046016  

Program:  Horizon Europe Framework Programme (HORIZON) Call COVID19 - HERA Incubator (HORIZON-HLTH-2021-CORONA-01)

 

Project Value: EUR 9 995 921 total budget, EUR 324 375 - is VUH Santaros klinikos project budget

Responsible Department at VUH Santaraos Klinikos: Hematology, Oncology and Transfusion Center

Project Manager: Daniel Naumovas

Project Purpose – to provide robust, data-driven evidence in the fight against SARS-CoV-2 strains and the COVID-19 epidemic, supported by immunological and virological studies and artificial intelligence components, focusing on hospital patients, vaccinated healthcare workers and school groups.

Project Co-ordinator: EURESIST NETWORK GEIE – EuResist (Italy)

Project Partners:

 KLINIKUM DER UNIVERSITAET ZU KOELN (UHC), Germany

UNIVERSITY COLLEGE LONDON (UCL),  United Kingdom

EBERHARD KARLS UNIVERSITAET TUEBINGEN (EKUT), Germany

UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA (UNITOV), Italy

KAROLINSKA INSTITUTET (KI), Sweden

UNIVERSITA DEGLI STUDI DI SIENA (UNISI), Italy

IBM ISRAEL - SCIENCE AND TECHNOLOGY LTD (IBM ISRAEL), Israel

AZIENDA SOCIO-SANITARIA TERRITORIALE (ASST) SANTI PAOLO E CARLO (ASST), Italy

ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE LAZZARO SPALLANZANI ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO (INMI), Italy

PI VILNIAUS UNIVERSITETO LIGONINE SANTAROS KLINIKOS (VULSK), Lithuania

ISTITUTO EUROPEO DI ONCOLOGIA SRL (IEO), Italy

UNIVERSIDADE NOVA DE LISBOA (UNL), Portugal

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE (Imperial), United Kingdom

INFECTIOUS DISEASES, AIDS AND CLINICAL IMMUNOLOGY RESEARCH CENTER (IDACIRC), Georgia

HEINRICH-HEINE-UNIVERSITAET DUESSELDORF (HHU), Germany

CENTRO HOSPITALAR DE LISBOA OCIDENTAL EPE (CHLO), Portugal,

ORGANIZING BUREAU OF EUROPEAN SCHOOL STUDENT UNIONS (OBESSU), Belgium

Project Start –  14 October 2021

Project End – 14 October 2026

 

CHIP-AML22 Improved diagnostics and survival for all children with Acute Myeloid Leukemia treated within the NOPHO-DB-SHIP consortium; a cross-European collaboration

 

CHIP-AML22  Improved diagnostics and survival for all children with Acute Myeloid Leukemia treated within the NOPHO-DB-SHIP consortium; a cross-European collaboration

Project No. 101079988

Program: EU4Health Programme (EU4H), Call: EU4H-2021-PJ2,  Topic: EU4H-2021-PJ-15

Project Value:  EUR 2 993 152.73 (financed 80% of the overall budget 2 394 522.13) total budget, EUR 69 800.38  (55 840.30Eur - is VUH Santaros klinikos project budget,

Responsible Department at VUH Santaraos Klinikos: Center for Pediatric Oncohematology, Pediatric Bone Marrow Transplantation Subsection

Project Manager: Ramunė Pasaulienė

Project Purpose – to find the targeted therapies for paediatric acute myeloid leukaemia (AML) patients.

CHIP-AML22 consortium aims to focus on three key areas:

  1. Genetic profiling of leukemic cells to identify subgroups of patients with prognostic indicators, which can help improve risk-group stratification across the consortium.
  2. Introducing tailored treatments based on gene activity information garnered from next-generation sequencing and transcriptome analysis of leukemic cells.
  3. Implementing and evaluating advanced treatment-response evaluations to further improve treatment outcomes.

In implementing these focus areas, the project aims to improve overall outcomes for all children with AML treated within the NOPHO-DB-SHIP (Nordic-Dutch-Belgian-Spain-Hong-Kong-Israel-Portugal) consortium. Its findings can provide valuable insights for a broader cohort of patients, including those with adult AML.

 

Project Co-ordinator: SKÅNES UNIVERSITY HOSPITAL (Sweden)

Project Partners:

SIHTASUTUS TALLINNA LASTEHAIGL (Estonia)

BERNU KLINISKA UNIVERSITATES SLIMNICA VALSTS SIA (Latvia)

VIESOJI ISTAIGA VILNIAUS UNIVERSITETO LIGONINE SANTAROS KLINIKOS (Lithuania)

OSLO UNIVERSITETSSYKEHUS HF (Norway)

FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA (Spain)

PRINSES MAXIMA CENTRUM VOOR KINDERONCOLOGIE BV (Netherlands)

AARHUS UNIVERSITETSHOSPITAL (Denmark)

REGION HOVEDSTADEN (Denmark)

PIRKANMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMA (Finland)

UNIVERSITEIT GENT (Belgium)

LANDSPITALI UNIVERSITY HOSPITAL (Iceland)

VÄSTRA GÖTALANDSREGIONEN (Sweden)

INSTITUTO PORTUGUES DE ONCOLOGIA DO PORTO FRANCISCO GENTIL, EPE (Portugal)

More info: https://vard.skane.se/en/skane-university-hospital/about-us/news/children-with-leukaemia-to-gain-access-to-equal-treatment-via-european-project-coordinated-by-skane-university-hospital/

Project Start – 01 November 2022

Project End – 31 October 2025

TBmikrobiomas - Lung microbiome study of Lithuanian tuberculosis patients
Project No. S-MIP-24-70

Program: Research Group Projects Call XIII
This project has received funding from Research Council of Lithuanian (Finance Agreement No. S-MIP-24-70)
 
Project Value: EUR 170 789,81 total budget, EUR 28 770,45 - is VUH Santaros klinikos project budget

Responsible Department at VUH Santaraos Klinikos: Pulmonology and Allergology Center

Project Manager: dr. Edita Davidavičienė, Head of the Tuberculosis State Information System Department

Project Purpose – To assess the influence of lung microbiome composition on the development of TB in Lithuanian residents newly diagnosed with TB, using large-scale sequencing analysis.

Main Tasks:
1. To investigate and compare the lung microbiome of patients with drug-susceptible and drug-resistant tuberculosis.
2. To compare the lung microbiome of patients with tuberculosis and other chronic lung diseases (chronic bronchitis chronic obstructive pulmonary disease).
3. To investigate possible associations between the composition of the lung microbiome and tuberculosis drug sensitivity (susceptible, resistant), duration of treatment, co-morbidities and other factors.

Project Co-ordinator: Vilnius Univeristy Faculty of Medicine

Project Partners: Vilnius University Hospital Santaros Klinikos, Vilnius University Life Science Center

Project Start – 24th October, 2024

Project End – 31st August, 2027
 
 
LYMPHOAI - Development of a minimally invasive and AI- based method for lymphoma monitoring

Project No. Nr. S-MIP-24-115 / KT2024-162

Program: Research Group Projects Call XIII

This project has received funding from Research Council of Lithuanian (Finance Agreement No.S-MIP-24-115 / KT2024-162)  

Project Value:  EUR 199 996,79 total budget, EUR 79 656,05 - is VUH Santaros klinikos project budget

Responsible Department at VUH Santaros Klinikos: Center for Hematology, Oncology and Transfusiology, Department of Molecular Medicine

Project Manager: Raminta Batiuškaitė, Medical Geneticist

Project Purpose – to create an AI-based molecular testing method that will allow sensitive and specific identification of gene alterations in ctDNA samples, thereby improving disease diagnostics, sensitivity of MRD, and early detection of disease relapse. 

This project consists of two main activities - the development of a lymphoma-specific ctDNA mutation analysis method, and the creation of an AI-based bioinformatics algorithm for more accurate detection of somatic mutations. 

During the project, we hope to develop a cost-effective methodology that can be applied to current clinical practice. This way we will contribute to lymphoma patients improving the quality of life. 

Project Co-ordinator: National Cancer Institute

Project Partner: VUH Santaraos Klinikos

Project Start – 8th November, 2024

Project End – 31st August, 2027

 

 

JA PREVENTNCD – CANCER AND OTHER NON-COMMUNICABLE DISEASES PREVENTION – ACTION ON HEALTH DETERMINANTS

Project No.: 101128023                       

Program: EU4Health European Joint Action Program on Non-Communicable Diseases, JAPreventNCD — EU4H-2022-JA-IBA

Project Value: 95 523 718,92 EUR  total budget (80% - 76 409 622,62 is co-funded by EU) , VUHSK received EU support 81 367,94 EUR

Responsible Department at VUH Santaraos Klinikos: Hematology, Oncology and Transfusion Medicine Center, Oncogenetics Division

Project Manager: Dr. Ramūnas Janavičius

Project Purpose: Cancer and other Non-Communicable Diseases (C&NCD) make up more than 2/3 of the burden of disease in Europe. At the population level, substantial variations exist according to socio-economic status, geographical area, age, disability, gender, and ethnic groups. A large part of this disease burden is preventable. The aim of the JA on Cancer and other NCDs prevention  to support strategies and policies designed to reduce the burden of cancer and NCDs, their common risk factors both at individual and societal level and to define methods to assess the effectiveness of prevention policies across Europe.

VUHSK participates in WP10  „Identify individuals at risk“ .The general objective of this work package is to reduce the burden of cancer and other NCDs mainly at the personal level by providing guidance and producing further evidence on integrating information from generic determinants, demographic, behavioral characteristics (individual-level-factors) into a holistic approach for c&NCDs prevention.

VUHSK participates in a pilot project whish aims to identify woomen having ovarian cancer risk at an earlier stage. The results based on genomic medicine will be proposed to integrated into the clinical practice of ovarian cancer prevention.

 

Project Co-ordinator: Norwegian Directorate of Health (HDIR), Norway

WP10 package leader - Sciensano ,Belgium and co-leader – RSYD, Denmark

Project Partners:  98 EU institutions  from 25 countries

Project Start – 1st January, 2024

Project End – 31st December, 2027

 

 

Last edited: 2024-12-16
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